The management of granulosa cell tumor of the ovary--a case history.

Granulosa cell tumors comprise 3% to 10%of all malignant ovarian tumors. They are diagnosed at all ages, but usually occur after the menopause [1]. The most common presenting symptom is abnormal uterine bleeding due to hormonal activity of the tumor. Complete surgical removal is the management of choice for these tumors. The stage at the initial operation appears to be the most important prognostic factor for cancerrelated survival. The management of metastatic disease or inoperable loco-regional relapse has yet to be defined for this uncommon ovarian tumor. The following case history illustrates a number of management problems in a patient with granulosa cell tumor of the ovary. Therapeutic options for the different stages of the disease will be discussed.